Scene Manager has a first-class, native integration with RenderFlow that no other render manager can match: submit dozens of setups from a single scene file in one click, with the file uploaded once and every setup resolved at render time.

For Deadline and Backburner, Scene Manager can bake setups into native 3ds Max batch render (submittable to either) or save each setup as a separate file for individual submission. You don't lose compatibility, but the RenderFlow workflow is dramatically faster.